Ontology highlight
ABSTRACT:
SUBMITTER: Akere A
PROVIDER: S-EPMC7419078 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Akere Aishat A Chen Serena H SH Liu Xiaohan X Chen Yanger Y Dantu Sarath Chandra SC Pandini Alessandro A Bhowmik Debsindhu D Haider Shozeb S
The Biochemical journal 20200801 15
Glycosylation of secondary metabolites involves plant UDP-dependent glycosyltransferases (UGTs). UGTs have shown promise as catalysts in the synthesis of glycosides for medical treatment. However, limited understanding at the molecular level due to insufficient biochemical and structural information has hindered potential applications of most of these UGTs. In the absence of experimental crystal structures, we employed advanced molecular modeling and simulations in conjunction with biochemical c ...[more]