Ontology highlight
ABSTRACT:
SUBMITTER: Huang A
PROVIDER: S-EPMC7419547 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Huang Ao A Yang Xin-Rong XR Chung Wen-Yuan WY Dennison Ashley R AR Zhou Jian J
Signal transduction and targeted therapy 20200811 1
The last 3 years have seen the emergence of promising targeted therapies for the treatment of hepatocellular carcinoma (HCC). Sorafenib has been the mainstay of treatment for a decade and newer modalities were ineffective and did not confer any increased therapeutic benefit until the introduction of lenvatinib which was approved based on its non-inferiority to sorafenib. The subsequent success of regorafenib in HCC patients who progress on sorafenib treatment heralded a new era of second-line tr ...[more]