Ontology highlight
ABSTRACT:
SUBMITTER: Liu Q
PROVIDER: S-EPMC7423571 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Liu Qipeng Q Wang Guangyu G Li Qiaqia Q Jiang Weihua W Kim Jung-Sun JS Wang Rui R Zhu Sen S Wang Xiaoju X Yan Lin L Yi Yang Y Zhang Lili L Meng Qingshu Q Li Chao C Zhao Dongyu D Qiao Yuanyuan Y Li Yong Y Gursel Demirkan B DB Chinnaiyan Arul M AM Chen Kaifu K Cao Qi Q
International journal of cancer 20190212 2
Polycomb group proteins are important epigenetic regulators for cell proliferation and differentiation, organ development, as well as initiation and progression of lethal diseases, including cancer. Upregulated Polycomb group proteins, including Enhancer of zeste homolog 2 (EZH2), promote proliferation, migration, invasion and metastasis of cancer cells, as well as self-renewal of cancer stem cells. In our study, we report that EZH2 and embryonic ectoderm development (EED) indicate respective di ...[more]