Predictors of COVID-19 outcome in Parkinson's disease.
Ontology highlight
ABSTRACT:
Methods: In order to describe the outcome of COVID-19 in multi-centre a cohort of PD patients and explore its potential predictors, we gathered the clinical information of 117 community-dwelling patients with COVID-19 followed in 21 tertiary centres in Italy, Iran, Spain, and the UK.
Results: Overall mortality was 19.7%, with a significant effect of co-occurrence of dementia, hypertension, and PD duration.
Conclusions: The frailty caused by advanced PD poses an increased risk of mortality during COVID-19.
SUBMITTER: Fasano A
PROVIDER: S-EPMC7424315 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Publications
Predictors of COVID-19 outcome in Parkinson's disease.
Fasano Alfonso A Elia Antonio E AE Dallocchio Carlo C Canesi Margherita M Alimonti Dario D Sorbera Chiara C Alonso-Canovas Araceli A Pezzoli Gianni G
Parkinsonism & related disorders 20200813
<h4>Introduction</h4>Specific pre-existing medical conditions (e.g. hypertension or obesity), advanced age and male sex appear linked to more severe manifestations of SARS Co-V2 infection, thus raising the question of whether Parkinson's disease (PD) poses an increased risk of morbidity and mortality in COVID-19 patients.<h4>Methods</h4>In order to describe the outcome of COVID-19 in multi-centre a cohort of PD patients and explore its potential predictors, we gathered the clinical information o ...[more]
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