Novel strain analysis informs about injury susceptibility of the corpus callosum to repeated impacts.

ABSTRACT: Increasing evidence for the cumulative effects of head trauma on structural integrity of the brain has emphasized the need to understand the relationship between tissue mechanic properties and injury susceptibility. Here, diffusion tensor imaging, helmet accelerometers and amplified magnetic resonance imaging were combined to gather insight about the region-specific vulnerability of the corpus callosum to microstructural changes in white-matter integrity upon exposure to sub-concussive impacts. A total of 33 male Canadian football players (mean_age = 20.3 ± 1.4 years) were assessed at three time points during a football season (baseline pre-season, mid-season and post-season). The athletes were split into a LOW (N = 16) and HIGH (N = 17) exposure group

SUBMITTER: Champagne AA 

PROVIDER: S-EPMC7425391 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature