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A social dancing pilot intervention for older adults at high risk for Alzheimer's disease and related dementias.


ABSTRACT: Close to 6 million older US adults have Alzheimer's disease or related dementias, yet there is currently no cure or effective treatment. This single-blind randomized controlled trial (clinicaltrials.gov: NCT03475316) aims to establish feasibility, and explore the relative efficacy, of a 6-month social ballroom dancing intervention versus a 6-month active control intervention (treadmill walking) for improving executive function in 32 older adults at increased risk for Alzheimer's disease or related dementias. Dementia-at-risk status is determined with cut-scores on the memory impairment screen (≥3 to ≤6) and/or the AD8 Dementia Screening Interview (≥1). The primary outcome is a composite executive function score from digit-symbol substitution, flanker interference and walking-while-talking tasks. The secondary outcome is functional neuroplasticity during fMRI-adapted versions of digit-symbol substitution, flanker interference and walking-while-talking.

SUBMITTER: Blumen HM 

PROVIDER: S-EPMC7426754 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature

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A social dancing pilot intervention for older adults at high risk for Alzheimer's disease and related dementias.

Blumen Helena M HM   Ayers Emmeline E   Wang Cuiling C   Ambrose Anne F AF   Verghese Joe J  

Neurodegenerative disease management 20200803 4


Close to 6 million older US adults have Alzheimer's disease or related dementias, yet there is currently no cure or effective treatment. This single-blind randomized controlled trial (clinicaltrials.gov: NCT03475316) aims to establish feasibility, and explore the relative efficacy, of a 6-month social ballroom dancing intervention versus a 6-month active control intervention (treadmill walking) for improving executive function in 32 older adults at increased risk for Alzheimer's disease or relat  ...[more]

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