Ontology highlight
ABSTRACT:
SUBMITTER: Zhao L
PROVIDER: S-EPMC7426866 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Zhao Lin L Abrigo Jill J Chen Qianyun Q Au Cheryl C Ng Angel A Fan Ping P Mok Vincent V Qiu Wei W Kermode Allan G AG Lau Alexander Y AY
Scientific reports 20200813 1
Oligoclonal IgG bands (OCB) in cerebrospinal fluid (CSF) are important in diagnosis of multiple sclerosis (MS). We evaluated the MRI features of clinically definite MS subjects with and without CSF-OCB. Relapsing MS subjects were recruited from a prospective registry in a university center. CSF-OCB were detected using isoelectric focusing and lgG-specific immunofixation. MRI metrics including brain volumes, lesion volumes and microstructural measures, were analyzed by FMRIB Software Library (FSL ...[more]