Ontology highlight
ABSTRACT:
SUBMITTER: Yamahira S
PROVIDER: S-EPMC7428233 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Yamahira Shinya S Satoh Taku T Yanagawa Fumiki F Tamura Masato M Takagi Toshiyuki T Nakatani Eri E Kusama Yuta Y Sumaru Kimio K Sugiura Shinji S Kanamori Toshiyuki T
Royal Society open science 20200701 7
Inside living organisms, concentration gradients dynamically change over time as biological processes progress. Therefore, methods to construct dynamic microscale concentration gradients in a spatially controlled manner are needed to provide more realistic research environments. Here, we report a novel method for the construction of dynamic microscale concentration gradients in a stepwise manner around cells in micropatterned hydrogel. In our method, cells are encapsulated in a photodegradable h ...[more]