Ontology highlight
ABSTRACT:
SUBMITTER: Wu X
PROVIDER: S-EPMC7428569 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Wu Xiaolin X Lin Lijin L Qin Juan-Juan JJ Wang Lifen L Wang Hao H Zou Yichun Y Zhu Xueyong X Hong Ying Y Zhang Yan Y Liu Ye Y Xin Can C Xu Shuangxiang S Ye Shengda S Zhang Jianjian J Xiong Zhongwei Z Zhu Lihua L Li Hongliang H Chen Jincao J She Zhi-Gang ZG
Journal of the American Heart Association 20200430 9
Background Although multiple signaling cascades and molecules contributing to the pathophysiological process have been studied, the treatments for stroke against present targets have not acquired significant clinical progress. Although CARD3 (caspase activation and recruitment domain 3) protein is an important factor involved in regulating immunity, inflammation, lipid metabolism, and apoptosis, its role in cerebral stroke is currently unknown. Methods and Results Using a mouse model of ischemia ...[more]