Study of Osteoarthritis-Related Hub Genes Based on Bioinformatics Analysis.
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ABSTRACT:
SUBMITTER: Zhu Z
PROVIDER: S-EPMC7428874 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Study of Osteoarthritis-Related Hub Genes Based on Bioinformatics Analysis.
Zhu Zhengqing Z Zhong Lei L Li Ronghang R Liu Yuzhe Y Chen Xiangrun X Li Zhaoyan Z Huang Lanfeng L
BioMed research international 20200805
Osteoarthritis (OA) is a common cause of morbidity and disability worldwide. However, the pathogenesis of OA is unclear. Therefore, this study was conducted to characterize the pathogenesis and implicated genes of OA. The gene expression profiles of GSE82107 and GSE55235 were downloaded from the Gene Expression Omnibus database. Altogether, 173 differentially expressed genes including 68 upregulated genes and 105 downregulated genes in patients with OA were selected based on the criteria of ∣log ...[more]
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