Ontology highlight
ABSTRACT:
SUBMITTER: Cheng L
PROVIDER: S-EPMC7428967 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Cheng Liangkai L Zhang Hong H Wu Fang F Liu Zhongqiu Z Cheng Yuanyuan Y Wang Caiyan C
Oxidative medicine and cellular longevity 20200805
Cardiocerebral vascular disease (CCVD) is a common disease with high morbidity, disability, and mortality. Oxidative stress (OS) is closely related to the progression of CCVD. Abnormal redox regulation leads to OS and overproduction of reactive oxygen species (ROS), which can cause biomolecular and cellular damage. The Nrf2/antioxidant response element (ARE) signaling pathway is one of the most important defense systems against exogenous and endogenous OS injury, and Nrf2 is regarded as a vital ...[more]