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Non-operative management of rectal cancer.


ABSTRACT: Despite advances in technique, surgical resection of rectal cancer remains a morbid procedure that can lead a profound decrease in a patient's quality of life. A novel method of management, termed "Non-operative management" (NOM), mirrors the management of anal carcinoma. Patients undergo definitive treatment with only chemotherapy and radiation, with resection reserved only for salvage. Current data is encouraging- both in reduction in morbidity and similar, if not superior oncologic results. However, there are a number of barriers to the wide adoption of this practice. This manuscript seeks to describe the rationale and execution of NOM as well as present the current data and pitfalls of the approach.

SUBMITTER: Greer JB 

PROVIDER: S-EPMC7431003 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature

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Non-operative management of rectal cancer.

Greer Jonathan B JB   Hawkins Alexander T AT  

Seminars in colon & rectal surgery 20190420 2


Despite advances in technique, surgical resection of rectal cancer remains a morbid procedure that can lead a profound decrease in a patient's quality of life. A novel method of management, termed "Non-operative management" (NOM), mirrors the management of anal carcinoma. Patients undergo definitive treatment with only chemotherapy and radiation, with resection reserved only for salvage. Current data is encouraging- both in reduction in morbidity and similar, if not superior oncologic results. H  ...[more]

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