Ontology highlight
ABSTRACT:
SUBMITTER: Trezza A
PROVIDER: S-EPMC7431416 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Trezza Alfonso A Iovinelli Daniele D Santucci Annalisa A Prischi Filippo F Spiga Ottavia O
Scientific reports 20200817 1
The Coronavirus disease 2019 (COVID-19) is an infectious disease caused by the severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2). The virus has rapidly spread in humans, causing the ongoing Coronavirus pandemic. Recent studies have shown that, similarly to SARS-CoV, SARS-CoV-2 utilises the Spike glycoprotein on the envelope to recognise and bind the human receptor ACE2. This event initiates the fusion of viral and host cell membranes and then the viral entry into the host cell. Despit ...[more]