Ontology highlight
ABSTRACT:
SUBMITTER: Kurihara-Shimomura M
PROVIDER: S-EPMC7432510 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Kurihara-Shimomura Miyako M Sasahira Tomonori T Shimomura Hiroyuki H Kirita Tadaaki T
International journal of molecular sciences 20200730 15
Despite dramatic progress in cancer diagnosis and treatment, the five-year survival rate of oral squamous cell carcinoma (OSCC) is still only about 50%. Thus, the need for elucidating the molecular mechanisms underlying OSCC is urgent. We previously identified the peroxidasin gene (<i>PXDN</i>) as one of several novel genes associated with OSCC. Although the PXDN protein is known to act as a tumor-promoting factor associated with the Warburg effect, its function and role in OSCC are poorly under ...[more]