Ontology highlight
ABSTRACT:
SUBMITTER: Kajitani R
PROVIDER: S-EPMC7433917 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Kajitani Rei R Yoshimura Dai D Ogura Yoshitoshi Y Gotoh Yasuhiro Y Hayashi Tetsuya T Itoh Takehiko T
DNA research : an international journal for rapid publication of reports on genes and genomes 20200601 3
De novo assembly of short DNA reads remains an essential technology, especially for large-scale projects and high-resolution variant analyses in epidemiology. However, the existing tools often lack sufficient accuracy required to compare closely related strains. To facilitate such studies on bacterial genomes, we developed Platanus_B, a de novo assembler that employs iterations of multiple error-removal algorithms. The benchmarks demonstrated the superior accuracy and high contiguity of Platanus ...[more]