Ontology highlight
ABSTRACT:
SUBMITTER: Xin F
PROVIDER: S-EPMC7435249 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Xin Fei F Zhou Xinqi X Dong Debo D Zhao Zhongbo Z Yang Xi X Wang Qianqian Q Gu Yan Y Kendrick Keith M KM Chen Antao A Becker Benjamin B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 20200701 16
The ability to successfully regulate negative emotions such as fear and anxiety is vital for mental health. Intranasal administration of the neuropeptide oxytocin (OXT) has been shown to reduce amygdala activity but to increase amygdala-prefrontal cortex connectivity during exposure to threatening stimuli suggesting that it may act as an important modulator of emotion regulation. The present randomized, between-subject, placebo-controlled pharmacological study combines the intranasal administrat ...[more]