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Metformin versus the combined oral contraceptive pill for hirsutism, acne, and menstrual pattern in polycystic ovary syndrome.


ABSTRACT:

SUBMITTER: Fraison E 

PROVIDER: S-EPMC7437400 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature

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Metformin versus the combined oral contraceptive pill for hirsutism, acne, and menstrual pattern in polycystic ovary syndrome.

Fraison Eloise E   Kostova Elena E   Moran Lisa J LJ   Bilal Sophia S   Ee Carolyn C CC   Venetis Christos C   Costello Michael F MF  

The Cochrane database of systematic reviews 20200813


<h4>Background</h4>Metformin has been proposed as possibly a safer and more effective long-term treatment than the oral contraceptive pill (OCP) in women with polycystic ovary syndrome (PCOS). It is important to directly compare the efficacy and safety of metformin versus OCP in the long-term treatment of women with PCOS. This is an update of a Cochrane Review comparing insulin sensitising agents with the OCP and only includes studies on metformin.<h4>Objectives</h4>To assess the effectiveness a  ...[more]

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