Ontology highlight
ABSTRACT:
SUBMITTER: Buegler M
PROVIDER: S-EPMC7437401 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Buegler Maximilian M Harms Robbert R Balasa Mircea M Meier Irene B IB Exarchos Themis T Rai Laura L Boyle Rory R Tort Adria A Kozori Maha M Lazarou Eutuxia E Rampini Michaela M Cavaliere Carlo C Vlamos Panagiotis P Tsolaki Magda M Babiloni Claudio C Soricelli Andrea A Frisoni Giovanni G Sanchez-Valle Raquel R Whelan Robert R Merlo-Pich Emilio E Tarnanas Ioannis I
Alzheimer's & dementia (Amsterdam, Netherlands) 20200819 1
<h4>Background</h4>Research investigating treatments and interventions for cognitive decline fail due to difficulties in accurately recognizing behavioral signatures in the presymptomatic stages of the disease. For this validation study, we took our previously constructed digital biomarker-based prognostic models and focused on generalizability and robustness of the models.<h4>Method</h4>We validated prognostic models characterizing subjects using digital biomarkers in a longitudinal, multi-site ...[more]