Dataset Information

Current Perspectives and Unmet Needs of Primary Immunodeficiency Care in Asia Pacific.

ABSTRACT: Background: The Asia Pacific Society for Immunodeficiencies (APSID) conducted nine primary immunodeficiency (PID) Schools in 5 years since inauguration to provide PID care training for early career physicians in Asia Pacific, a region with divergent needs in PID resources and training. Objective: To identify differences in PID patient care resource and training needs across Asia Pacific and propose a corresponding action plan. Methods: The Human Development Index (HDI) indicates the degree of socio-economic development in each country/region. Information related to investigations and learning issues were extracted from the abstracts and personal statements from all Schools and mapped onto resource and training needs. Correlations between HDI and country/region-specific parameters were tested by two-tailed Pearson correlation. Results: A total of 427 abstracts were received in nine Schools between 2015 and 2020, predominantly on immunodeficiencies affecting cellular and humoral immunity. Genetic confirmation was described in 61.8% of abstracts, and its absence negatively correlated with HDI (r = -0.696, p = 0.004). Essential immunologic and genetic tests were not available in 25.4 and 29.5% of abstracts, respectively, and their absence negatively correlated with HDI (r = -0.788, p < 0.001; r = -0.739, p = 0.002). HDI positively correlated with average testing level (r = 0.742, p = 0.002). Cases from medium-HDI countries/regions focused on learning how to investigate a patient for PIDs in cases of severe or atypical infections, whereas those from very-high-HDI countries/regions, from which most faculty members originated, listed hematopoietic stem cell transplantation and gene therapy, newborn screening, and research as learning issues more frequently. Conclusion: There are unique HDI-related PID resource and training needs in each country/region. APSID proposes HDI group-specific strategies to improve PID care and education in her member countries/regions. Further quantitative analysis of needs in PID care in Asia Pacific is needed for lobbying governments to increase their support for PID care and research.

SUBMITTER: Leung D

PROVIDER: S-EPMC7438539 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

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Current Perspectives and Unmet Needs of Primary Immunodeficiency Care in Asia Pacific.

Leung Daniel D Chua Gilbert T GT Mondragon Alric V AV Zhong Youjia Y Nguyen-Ngoc-Quynh Le L Imai Kohsuke K Vignesh Pandiarajan P Suratannon Narissara N Mao Huawei H Lee Wen-I WI Kim Yae-Jean YJ Chan Godfrey C F GCF Liew Woei Kang WK Huong Le Thi Minh LTM Kanegane Hirokazu H Muktiarti Dina D Zhao Xiaodong X Santos-Ocampo Fatima Johanna FJ Latiff Amir Hamzah Abdul AHA Seger Reinhard R Ochs Hans D HD Singh Surjit S Lee Pamela P PP Lau Yu Lung YL

Frontiers in immunology 20200813

Background: The Asia Pacific Society for Immunodeficiencies (APSID) conducted nine primary immunodeficiency (PID) Schools in 5 years since inauguration to provide PID care training for early career physicians in Asia Pacific, a region with divergent needs in PID resources and training. Objective: To identify differences in PID patient care resource and training needs across Asia Pacific and propose a corresponding action plan. Methods: The Human Development Index (HDI) indic ...[more]

PMID: 32903579

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Dataset Information

Current Perspectives and Unmet Needs of Primary Immunodeficiency Care in Asia Pacific.

Publications

Current Perspectives and Unmet Needs of Primary Immunodeficiency Care in Asia Pacific.

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