RNase T2 in Inflammation and Cancer: Immunological and Biological Views.
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ABSTRACT:
SUBMITTER: Wu L
PROVIDER: S-EPMC7438567 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
RNase T2 in Inflammation and Cancer: Immunological and Biological Views.
Wu Lei L Xu Yanquan Y Zhao Huakan H Li Yongsheng Y
Frontiers in immunology 20200813
The RNase T2 family consists of evolutionarily conserved endonucleases that express in many different species, including animals, plants, protozoans, bacteria, and viruses. The main biological roles of these ribonucleases are cleaving or degrading RNA substrates. They preferentially cleave single-stranded RNA molecules between purine and uridine residues to generate two nucleotide fragments with 2'3'-cyclic phosphate adenosine/guanosine terminus and uridine residue, respectively. Accumulating st ...[more]
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