Ontology highlight
ABSTRACT:
SUBMITTER: Gray SP
PROVIDER: S-EPMC7439918 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Vascular biology (Bristol, England) 20190711 1
The heart relies on complex mechanisms that provide adequate myocardial oxygen supply in order to maintain its contractile function. At the cellular level, oxygen undergoes one electron reduction to superoxide through the action of different types of oxidases (e.g. xanthine oxidases, uncoupled nitric oxide synthases, NADPH oxidases or NOX). Locally generated oxygen-derived reactive species (ROS) are involved in various signaling pathways including cardiac adaptation to different types of physiol ...[more]