Dataset Information

Spatio-temporal estimation of the daily cases of COVID-19 in worldwide using random forest machine learning algorithm.

ABSTRACT: Novel Coronavirus pandemic, which negatively affected public health in social, psychological and economical terms, spread to the whole world in a short period of 6 months. However, the rate of increase in cases was not equal for every country. The measures implemented by the countries changed the daily spreading speed of the disease. This was determined by changes in the number of daily cases. In this study, the performance of the Random Forest (RF) machine learning algorithm was investigated in estimating the near future case numbers for 190 countries in the world and it is mapped in comparison with actual confirmed cases results. The number of confirmed cases between 23/01/2020 - 17/06/2020 were divided into 3 main sub-datasets: training sub-data, testing sub-data (interpolation data) and estimating sub-data (extrapolation data) for the random forest model. At the end of the study, it has been found that R² values for testing sub-data of RF model estimates range between 0.843 and 0.995 (average R²= 0.959), and RMSE values between 141.76 and 526.18 (mean RMSE = 259.38); and that R² values for estimating sub-data range between 0.690 and 0.968 (mean R² = 0.914), and RMSE values between 549.73 and 2500.79 (mean RMSE = 909.37). These results show that the random forest machine learning algorithm performs well in estimating the number of cases for the near future in case of an epidemic like Novel Coronavirus, which outbreaks suddenly and spreads rapidly.

SUBMITTER: YeSIlkanat CM

PROVIDER: S-EPMC7439995 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature

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Spatio-temporal estimation of the daily cases of COVID-19 in worldwide using random forest machine learning algorithm.

YeŞİlkanat Cafer Mert CM

Chaos, solitons, and fractals 20200820

Novel Coronavirus pandemic, which negatively affected public health in social, psychological and economical terms, spread to the whole world in a short period of 6 months. However, the rate of increase in cases was not equal for every country. The measures implemented by the countries changed the daily spreading speed of the disease. This was determined by changes in the number of daily cases. In this study, the performance of the Random Forest (RF) machine learning algorithm was investigated in ...[more]

PMID: 32843823

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Project description:Random forest and similar Machine Learning techniques are already used to generate spatial predictions, but spatial location of points (geography) is often ignored in the modeling process. Spatial auto-correlation, especially if still existent in the cross-validation residuals, indicates that the predictions are maybe biased, and this is suboptimal. This paper presents a random forest for spatial predictions framework (RFsp) where buffer distances from observation points are used as explanatory variables, thus incorporating geographical proximity effects into the prediction process. The RFsp framework is illustrated with examples that use textbook datasets and apply spatial and spatio-temporal prediction to numeric, binary, categorical, multivariate and spatiotemporal variables. Performance of the RFsp framework is compared with the state-of-the-art kriging techniques using fivefold cross-validation with refitting. The results show that RFsp can obtain equally accurate and unbiased predictions as different versions of kriging. Advantages of using RFsp over kriging are that it needs no rigid statistical assumptions about the distribution and stationarity of the target variable, it is more flexible towards incorporating, combining and extending covariates of different types, and it possibly yields more informative maps characterizing the prediction error. RFsp appears to be especially attractive for building multivariate spatial prediction models that can be used as "knowledge engines" in various geoscience fields. Some disadvantages of RFsp are the exponentially growing computational intensity with increase of calibration data and covariates and the high sensitivity of predictions to input data quality. The key to the success of the RFsp framework might be the training data quality-especially quality of spatial sampling (to minimize extrapolation problems and any type of bias in data), and quality of model validation (to ensure that accuracy is not effected by overfitting). For many data sets, especially those with lower number of points and covariates and close-to-linear relationships, model-based geostatistics can still lead to more accurate predictions than RFsp.

Project description:Background and aimsThis study aimed to develop an interpretable random forest model for predicting severe acute pancreatitis (SAP).MethodsClinical and laboratory data of 648 patients with acute pancreatitis were retrospectively reviewed and randomly assigned to the training set and test set in a 3:1 ratio. Univariate analysis was used to select candidate predictors for the SAP. Random forest (RF) and logistic regression (LR) models were developed on the training sample. The prediction models were then applied to the test sample. The performance of the risk models was measured by calculating the area under the receiver operating characteristic (ROC) curves (AUC) and area under precision recall curve. We provide visualized interpretation by using local interpretable model-agnostic explanations (LIME).ResultsThe LR model was developed to predict SAP as the following function: -1.10-0.13×albumin (g/L) + 0.016 × serum creatinine (μmol/L) + 0.14 × glucose (mmol/L) + 1.63 × pleural effusion (0/1)(No/Yes). The coefficients of this formula were utilized to build a nomogram. The RF model consists of 16 variables identified by univariate analysis. It was developed and validated by a tenfold cross-validation on the training sample. Variables importance analysis suggested that blood urea nitrogen, serum creatinine, albumin, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, calcium, and glucose were the most important seven predictors of SAP. The AUCs of RF model in tenfold cross-validation of the training set and the test set was 0.89 and 0.96, respectively. Both the area under precision recall curve and the diagnostic accuracy of the RF model were higher than that of both the LR model and the BISAP score. LIME plots were used to explain individualized prediction of the RF model.ConclusionsAn interpretable RF model exhibited the highest discriminatory performance in predicting SAP. Interpretation with LIME plots could be useful for individualized prediction in a clinical setting. A nomogram consisting of albumin, serum creatinine, glucose, and pleural effusion was useful for prediction of SAP.

Dataset Information

Spatio-temporal estimation of the daily cases of COVID-19 in worldwide using random forest machine learning algorithm.

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Spatio-temporal estimation of the daily cases of COVID-19 in worldwide using random forest machine learning algorithm.

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