Ontology highlight
ABSTRACT:
SUBMITTER: Goto H
PROVIDER: S-EPMC7441082 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Goto Hideki H Makita Shinichi S Kato Koji K Tokushige Kota K Fujita Taizo T Akashi Koichi K Izutsu Koji K Teshima Takanori T
International journal of clinical oncology 20200524 9
<h4>Background</h4>Tisagenlecleucel demonstrated a high rate of durable response in adult patients with relapsed/refractory (r/r) diffuse large B-cell lymphoma (DLBCL) in the pivotal global phase 2 JULIET study. Here, we report the efficacy and safety of tisagenlecleucel in the Japanese subgroup.<h4>Methods</h4>JULIET (NCT02445248) is a single-arm, open-label, multicenter, phase 2 study involving adult patients with r/r DLBCL who either relapsed after or were ineligible for autologous stem cell ...[more]