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Implementing Fixed Dose Combination Medications for the Prevention and Control of Cardiovascular Diseases.


ABSTRACT: Highlights:  - Despite clinical evidence of its effectiveness in secondary prevention of cardiovascular disease, uptake of fixed dose combination therapy (FDCs) for CVD has been poor.- A symposium was held bringing together stakeholders on this issue, including from academia, government and NGOs.- The conclusion made was that what is now needed to improve implementation of FDCs is country-specific health systems analyses to design appropriate implementation strategies.- Implementation strategies must look beyond listing on the WHO Essential Medicines List to consider approaches to improving FDC availability, accessibility, affordability, and adherence.- Strategies might include incorporation of FDCs into the WHO HEARTS technical package, simplified treatment and monitoring algorithms, decentralisation of medicine dispensing and task-sharing for treatment management.

SUBMITTER: Webster R 

PROVIDER: S-EPMC7442173 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature

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Implementing Fixed Dose Combination Medications for the Prevention and Control of Cardiovascular Diseases.

Webster Ruth R   Murphy Adrianna A   Bygrave Helen H   Ansbro Éimhín É   Grobbee Diederick E DE   Perel Pablo P  

Global heart 20200819 1


<b>Highlights:</b>  - Despite clinical evidence of its effectiveness in secondary prevention of cardiovascular disease, uptake of fixed dose combination therapy (FDCs) for CVD has been poor.- A symposium was held bringing together stakeholders on this issue, including from academia, government and NGOs.- The conclusion made was that what is now needed to improve implementation of FDCs is country-specific health systems analyses to design appropriate implementation strategies.- Implementation str  ...[more]

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