All-Cause Mortality and Causes of Death in the Swiss Hepatitis C Cohort Study (SCCS).

ABSTRACT:

Background

With direct-acting antiviral agents (DAAs), mortality rates and causes of death among persons with hepatitis C virus (HCV) infection may change over time. However, the emergence of such trends may be delayed by the slow progression of chronic hepatitis C. To date, detailed analyses of cause-specific mortality among HCV-infected persons over time remain limited.

Methods

We evaluated changes in causes of death among Swiss Hepatitis C Cohort Study (SCCS) participants from 2008 to 2016. We analyzed risk factors for all-cause and cause-specific mortality, accounting for changes in treatment, fibrosis stage, and use of injectable drugs over time. Mortality ascertainment was completed by linking lost-to-follow-up participants to the Swiss Federal Statistical Office death

SUBMITTER: Roelens M 

PROVIDER: S-EPMC7443104 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature