Ontology highlight
ABSTRACT:
SUBMITTER: Zou WJ
PROVIDER: S-EPMC7445164 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Zou Wen-Jun WJ Song Yun-Long YL Wu Min-Yi MY Chen Xiang-Tian XT You Qiang-Long QL Yang Qian Q Luo Zheng-Yi ZY Huang Lang L Kong Yin Y Feng Jing J Fang Dong-Xiang DX Li Xiao-Wen XW Yang Jian-Ming JM Mei Lin L Gao Tian-Ming TM
Nature communications 20200824 1
Exposure to social stress and dysregulated serotonergic neurotransmission have both been implicated in the etiology of psychiatric disorders. However, the serotonergic circuit involved in stress vulnerability is still unknown. Here, we explored whether a serotonergic input from the dorsal raphe (DR) to ventral tegmental area (VTA) influences vulnerability to social stress. We identified a distinct, anatomically and functionally defined serotonergic subpopulation in the DR that projects to the VT ...[more]