Periconceptional stressors and social support and risk for adverse birth outcomes.
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ABSTRACT:
SUBMITTER: Weber KA
PROVIDER: S-EPMC7446063 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Publications
Periconceptional stressors and social support and risk for adverse birth outcomes.
Weber Kari A KA Carmichael Suzan L SL Yang Wei W Tinker Sarah C SC Shaw Gary M GM
BMC pregnancy and childbirth 20200824 1
<h4>Background</h4>The prevalence of preterm birth and low birth weight has been increasing slightly in recent years. A few studies have suggested that psychosocial stress during pregnancy may increase risk for these adverse birth outcomes. To extend those observations, we analyzed various major life event stressors separately and cumulatively as potential risk factors for preterm birth and low birth weight using granular categories of each outcome in a large, population-based study. Additionall ...[more]
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Project description:BackgroundOver decades, obstetricians have evaluated a range of risk factors to improve the prediction of adverse birth outcomes.ObjectiveThis study aimed to assess the effectiveness of the Child-Mother Index as a risk factor indicator for selected adverse maternal birth outcomes.Study designWe assessed the Child-Mother Index by multinomial regression models using register-based data containing all singleton births in Denmark in 2009 with a gestational age between 37+0 and 41+6 weeks. The Child-Mother Index is defined as the weight of the newborn divided by the squared maternal height.ResultsData from 47,007 births were included. Both the Child-Mother Index mean and Child-Mother Index median were 12.6 hg/m2 (range, 4.8-22.4). In the multivariable model, the relative risk ratios for Child-Mother Index above 14.1 hg/m2 were 2.2 (95% confidence interval, 1.6-3.1) for third- and fourth-degree perineal tears, 2.0 (1.6-2.5) for nonelective cesarean delivery, and 1.0 (0.8-1.3) for instrumental procedures. Equivalent figures for a Child-Mother Index below 11.2 hg/m2 were 0.6 (0.4-1.0), 1.0 (0.8-1.2), and 0.7 (0.6-0.9), respectively.By comparing a multivariable model with the Child-Mother Index included with a model without the Child-Mother Index included using a likelihood ratio test, a statistically significant difference was found in favor of the Child-Mother Index inclusion (P<.001).ConclusionThe Child-Mother Index constitutes a potential useful risk factor indicator for statistical analyses on data after birth. The value of the Child-Mother Index based on the estimated fetal weight before birth deserves evaluation.
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