Ontology highlight
ABSTRACT:
SUBMITTER: Baker CJ
PROVIDER: S-EPMC7446893 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
PloS one 20200821 8
Investigation of the biological roles of inorganic polyphosphate has been facilitated by our previous development of a carbodiimide-based method for covalently coupling primary amine-containing molecules to the terminal phosphates of polyphosphate. We now extend that approach by optimizing the reaction conditions and using readily available "bridging molecules" containing a primary amine and an additional reactive moiety, including another primary amine, a thiol or a click chemistry reagent such ...[more]