Peripherally inserted central venous catheter (PICC) in outpatient and inpatient oncological treatment.

ABSTRACT: PURPOSE:So far there is little evidence on peripherally inserted central venous catheter (PICC) in radiation oncology patients maintaining the access during the periods of ambulatory and hospital treatment. METHODS:A total of 522 PICC placements in 484 patients were performed between 11/2011 and 07/2016 at the Department of Radiation Oncology and analysed retrospectively for complications and treatment- and patient-related factors during ambulatory and hospital inpatient use. On initial hospitalization, all patients received a multimodal radio-oncological treatment consisting of radiation and intravenous therapy administered via the PICC. RESULTS:A total of 18,292 catheter days were documented. Median follow-up from catheter insertion to their removal was 37 days (1-97). The overall complication rate was 4.1 per 1000 catheter days (n?=?75, 14.4%). Complications were similar between the cohort of outpatient 3.6 per 1000 catheter days and the cohort of inpatient 4.8 per 1000 catheter days (OR 0.976; 95% CI [0.598; 1.619]; p?=?0.924). Severe bloodstream infections occurred at a rate of 0.60 per 1000 catheter days (n?=?11, 2.1%), deep vein thrombosis at a rate of 0.82 per 1.000 catheter days (n?=?15, 2.9%) and local inflammation at a rate of 1.26 per 1.000 catheter days (n?=?23, 4.4%). Only immunotherapy could be identified as an independent risk factor for complications (OR 5.6; 95% CI [2.4; 13.1]; p?

SUBMITTER: Mielke D 

PROVIDER: S-EPMC7447660 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature