Feasibility of dual-task gait to estimate Alzheimer's related cognitive decline in Down syndrome.
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ABSTRACT:
SUBMITTER: Van Pelt KL
PROVIDER: S-EPMC7447907 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Feasibility of dual-task gait to estimate Alzheimer's related cognitive decline in Down syndrome.
Van Pelt Kathryn L KL Koehl Lisa L Caban-Holt Allison A Anderson-Mooney Amelia A Head Elizabeth E Schmitt Frederick A FA
Alzheimer's & dementia (Amsterdam, Netherlands) 20200825 1
<h4>Introduction</h4>The striatum and frontal lobes have been shown to have early Alzheimer's disease (AD) neuropathology and are critical for motor and cognitive function. We hypothesized gait would be associated with early-stage dementia in Down syndrome (DS), a cohort at risk for AD.<h4>Methods</h4>Twenty-eight participants with DS were enrolled in the study. Participants walked at their self-selected pace and while completing a dual task (counting, obstacle, or counting+obstacle).<h4>Results ...[more]
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Project description: Not available
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