Ontology highlight
ABSTRACT:
SUBMITTER: Chen J
PROVIDER: S-EPMC7448123 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Chen Jincan J Wang Jie J Deng Yuanyuan Y Wang Tao T Miao Tifang T Li Chengpeng C Cai Xianhong X Liu Ying Y Henri Justin J Chen Lanmei L
Bioinorganic chemistry and applications 20200817
Two new Ru(II) complexes containing O, O-chelated ligands, Ru(dip)<sub>2</sub>(SA) (<b>Ru-1</b>) and Ru(dmp)<sub>2</sub>(SA) (<b>Ru-2</b>) (dip = 4,7-diphenyl-1,10-phenanthroline; dmp = 2,9-dimethyl-1,10-phenanthroline; SA = salicylate) were synthesized to evaluate their cytotoxicity <i>in vitro</i>. These complexes were found to exhibit moderate antitumor activity to different types of human cancers, including A549 (human lung carcinoma), MCF-7 (breast cancer), HeLa (human cervical cancer), and ...[more]