Potential prognostic value of delta-like protein 3 in small cell lung cancer: a meta-analysis.

ABSTRACT:

Background

Current researches have revealed that delta-like protein 3 (DLL3) may be related with prognosis in patients with small cell lung cancer (SCLC). However, this finding remains controversial in small cell lung cancer. This meta-analysis was systematically performed to evaluate the prognostic value of DLL3 in SCLC.

Methods

The PubMed, EMBASE and Web of Science databases were retrieved to collect the eligible references. Through Stata 15.0 software, we pooled hazard ratios (HR) with 95% confidence intervals (CI) by using random or fixed-effects models to evaluate the association between DLL3 and SCLC survival results.

Results

A total of 6 inter-related studies including 645 patients were qualified. After we removed 1 study, the remaining 5 studies including 601

SUBMITTER: Chen B 

PROVIDER: S-EPMC7448456 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature