Ontology highlight
ABSTRACT:
SUBMITTER: Niu S
PROVIDER: S-EPMC7449627 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Niu Siqiang S Chavda Kalyan D KD Wei Jie J Zou Chunhong C Marshall Steven H SH Dhawan Puneet P Wang Deqiang D Bonomo Robert A RA Kreiswirth Barry N BN Chen Liang L
mSphere 20200826 4
Ceftazidime-avibactam is a potent antibiotic combination against <i>Klebsiella pneumoniae</i> carbapenemase (KPC)-producing <i>Enterobacteriaceae</i> Here, we describe a unique ceftazidime-avibactam-resistant and carbapenem-susceptible <i>K. pneumoniae</i> strain harboring a novel <i>bla</i><sub>KPC-14</sub> variant. This strain was isolated from a New York City patient in 2003, which predates the introduction of avibactam. Despite resistance to ceftazidime-avibactam, the strain was susceptible ...[more]