The Functional Roles of IL-33/ST2 Axis in Ocular Diseases.
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ABSTRACT:
SUBMITTER: Qian Y
PROVIDER: S-EPMC7450335 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
The Functional Roles of IL-33/ST2 Axis in Ocular Diseases.
Mediators of inflammation 20200818
Interleukin-33 (IL-33), an important member of the IL-1 family, plays a pivotal role in regulating immune responses via combining with its receptor suppression of tumorigenicity 2 (ST2). We have already known IL-33/ST2 axis participates in the pathogenesis of various diseases, including liver diseases, renal diseases, and neurological diseases. Recently, emerging studies are indicating that IL-33/ST2 is also involved in a wide range of ocular diseases, such as allergic eye disease, keratitis and ...[more]
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