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Wound healing Activities of the bioactive compounds from Micrococcus sp. OUS9 isolated from marine water.


ABSTRACT: Marine species are increasingly important as a source of specific biological active metabolites. Marine species comprise almost half of global biodiversity. Oceans and sea are thus the biggest source of positive natural compounds that could be utilized in the pharmaceutical industry as functional constituents. In the present study was to find out the wound healing property of the bioactive compounds from Micrococcus sp. OUS9 isolated from marine source. The in vivo wound healing activity was studied using excision wound model. The KLUF 10 and KLUF13 ointment was prepared and used to determine wound healing activity in albino rats. Topical application of the ointment enhanced the contraction of wound in contrast with rat control group. KLUF13 had shown strong healing ability in wounds and had a positive influence on the various phases of wound repair.

SUBMITTER: Shanthi Kumari K 

PROVIDER: S-EPMC7451693 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature

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Wound healing Activities of the bioactive compounds from <i>Micrococcus</i> sp. OUS9 isolated from marine water.

Shanthi Kumari K K   Shivakrishna Pabba P   Ganduri V S Ramakrishna VSR  

Saudi journal of biological sciences 20200511 9


Marine species are increasingly important as a source of specific biological active metabolites. Marine species comprise almost half of global biodiversity. Oceans and sea are thus the biggest source of positive natural compounds that could be utilized in the pharmaceutical industry as functional constituents. In the present study was to find out the wound healing property of the bioactive compounds from <i>Micrococcus sp</i>. OUS9 isolated from marine source. The in vivo wound healing activity  ...[more]

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