Ontology highlight
ABSTRACT:
SUBMITTER: Zhang JY
PROVIDER: S-EPMC7452009 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Molecular therapy oncolytics 20200731
Relapse of cancer is associated with multidirectional differentiation and unrestricted proliferative replication potential of cancer stem cells. Herein, we propose the plastic differentiation strategy for irreversible differentiation of cancer stem cells; further, salinomycin and its newly constructed functional liposomes are used to implement this strategy. Whole gene, cancer stem cell-related RNA, and protein expression analyses reveal that salinomycin induces the cancer stem cells into normal ...[more]