Female rats are resilient to the behavioral effects of maternal separation stress and exhibit stress-induced neurogenesis.
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ABSTRACT:
SUBMITTER: Lee YJ
PROVIDER: S-EPMC7452405 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
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Female rats are resilient to the behavioral effects of maternal separation stress and exhibit stress-induced neurogenesis.
Lee Yan Jun YJ Koe Amelia S AS Ashokan Archana A Mitra Rupshi R
Heliyon 20200821 8
Early-life stress causes anxiogenesis and sensitivity of stress endocrine axis, facilitated by changes in the basolateral amygdala and hippocampal neurogenesis. In this report, we examined if male-like relationship between early-life stress and anxiety was recapitulated in female rats, along with related neurobiological substrates of the amygdala and the hippocampus. Maternal separation, a paradigm consistently utilized in male rats in most previously published scripts, did not cause similar beh ...[more]
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