Dataset on transcriptomic profiling of cholestatic liver injury in an in vitro and in vivo animal model.
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ABSTRACT:
SUBMITTER: Gijbels E
PROVIDER: S-EPMC7452704 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Publications
Dataset on transcriptomic profiling of cholestatic liver injury in an <i>in vitro</i> and <i>in vivo</i> animal model.
Gijbels Eva E Devisscher Lindsey L Vinken Mathieu M
Data in brief 20200807
The transcriptomic dataset (whole genome microarray Affymetrix Human U133 plus 2.0 and Affymetrix Mouse Genome 430 2.0) presented in this paper describes the differential gene expression profile of a human <i>in vitro</i> model of drug-induced cholestasis and a well-known mouse <i>in vivo</i> model of cholestasis. The <i>in vitro</i> model consists of human hepatoma HepaRG cells in monolayer configuration exposed to 3 different cholestatic drugs with or without bile acids. For <i>in vivo</i> mod ...[more]
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