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Alterations in power spectral density in motor- and pain-related networks on neuropathic pain after spinal cord injury.


ABSTRACT: BACKGROUND:The mechanisms by which mobility function and neuropathic pain are mutually influenced by supraspinal plasticity in motor- and pain-related brain networks following spinal cord injury (SCI) remains poorly understood. OBJECTIVE:To determine cortical and subcortical resting-state network alterations using power spectral density (PSD) analysis and investigate the relationships between these intrinsic alterations and mobility function and neuropathic pain following SCI. METHODS:A total of 41 patients with incomplete SCI and 33 healthy controls were included. The degree of mobility and balance function and severity of neuropathic pain and depressive mood were evaluated. The resting-state functional magnetic resonance imaging data of low-frequency fluctuations were analyzed based on PSD. Differences in PSD values between patients with SCI and controls were assessed using the two-sample t-test (false discovery rate-corrected P?

SUBMITTER: Park E 

PROVIDER: S-EPMC7453139 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature

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Alterations in power spectral density in motor- and pain-related networks on neuropathic pain after spinal cord injury.

Park Eunhee E   Cha Hyunsil H   Kim Eunji E   Min Yu-Sun YS   Kim Ae Ryoung AR   Lee Hui Joong HJ   Jung Tae-Du TD   Chang Yongmin Y  

NeuroImage. Clinical 20200725


<h4>Background</h4>The mechanisms by which mobility function and neuropathic pain are mutually influenced by supraspinal plasticity in motor- and pain-related brain networks following spinal cord injury (SCI) remains poorly understood.<h4>Objective</h4>To determine cortical and subcortical resting-state network alterations using power spectral density (PSD) analysis and investigate the relationships between these intrinsic alterations and mobility function and neuropathic pain following SCI.<h4>  ...[more]

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