Ontology highlight
ABSTRACT:
SUBMITTER: Miodragovic Ð
PROVIDER: S-EPMC7453736 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Miodragović Ðenana Ð Swindell Elden P EP Waxali Zohra Sattar ZS Bogachkov Abraham A O'Halloran Thomas V TV
Inorganica chimica acta 20190724
Platinum drugs (cisplatin, oxaliplatin, and carboplatin) and arsenic trioxide are the only commercial inorganic non-radioactive anticancer drugs approved by the US Food and Drug Administration. Numerous efforts are underway to take advantage of the synergy between the anticancer activity of cisplatin and arsenic trioxide - two drugs with strikingly different mechanisms of action. These include co-encapsulation of the two drugs in novel nanoscale delivery systems as well as the development of sma ...[more]