Ontology highlight
ABSTRACT:
SUBMITTER: Shendy NAM
PROVIDER: S-EPMC7455715 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Shendy Noha Ahmed Mohammed NAM Raghu Deepthi D Roy Sujoy S Perry Charles Hamilton CH Safi Adiba A Branco Miguel Ramos MR Homayouni Ramin R Abell Amy Noel AN
Communications biology 20200828 1
Coordinated gene expression is required for phenotypic switching between epithelial and mesenchymal phenotypes during normal development and in disease states. Trophoblast stem (TS) cells undergo epithelial-mesenchymal transition (EMT) during implantation and placentation. Mechanisms coordinating gene expression during these processes are poorly understood. We have previously demonstrated that MAP3K4-regulated chromatin modifiers CBP and HDAC6 each regulate thousands of genes during EMT in TS ce ...[more]