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Prevalence and outcomes of re-positive nucleic acid tests in discharged COVID-19 patients.


ABSTRACT: The prevalence and outcomes of patients who had re-activation of coronavirus disease 2019 (COVID-19) after discharge remain poorly understood. We included 126 consecutively confirmed cases of COVID-19 with 2-month follow-up data after discharge in this retrospective study. The upper respiratory specimen using a reverse-transcription polymerase chain reaction test of three patients (71 years [60-76]) were positive within 11-20 days after their discharge, with an event rate of 19.8 (95%CI 2.60-42.1) per 1,000,000 patient-days. Moreover, all re-positive patients were asymptomatic. Our findings suggest that few recovered patients may still be virus carriers even after reaching the discharge criteria.

SUBMITTER: Du HW 

PROVIDER: S-EPMC7456660 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature

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Prevalence and outcomes of re-positive nucleic acid tests in discharged COVID-19 patients.

Du Hou-Wei HW   Chen Jun-Nian JN   Pan Xiao-Bin XB   Chen Xiao-Ling XL   Yixian-Zhang   Fang Shuang-Fang SF   Li Xiao-Qing XQ   Xia Pin-Cang PC   Gao Lei L   Lin Hai-Long HL   Chen Li-Min LM   Liu Nan N  

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20200831 2


The prevalence and outcomes of patients who had re-activation of coronavirus disease 2019 (COVID-19) after discharge remain poorly understood. We included 126 consecutively confirmed cases of COVID-19 with 2-month follow-up data after discharge in this retrospective study. The upper respiratory specimen using a reverse-transcription polymerase chain reaction test of three patients (71 years [60-76]) were positive within 11-20 days after their discharge, with an event rate of 19.8 (95%CI 2.60-42.  ...[more]

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