Ontology highlight
ABSTRACT:
SUBMITTER: Butler TD
PROVIDER: S-EPMC7456996 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Butler Thomas D TD Gibbs Julie E JE
Frontiers in immunology 20200814
The gut microbiome plays a critical role in regulating host immunity and can no longer be regarded as a bystander in human health and disease. In recent years, circadian (24 h) oscillations have been identified in the composition of the microbiota, its biophysical localization within the intestinal tract and its metabolic outputs. The gut microbiome and its key metabolic outputs, such as short chain fatty acids and tryptophan metabolites contribute to maintenance of intestinal immunity by promot ...[more]