Unknown

Dataset Information

0

Temporal Detection and Phylogenetic Assessment of SARS-CoV-2 in Municipal Wastewater.


ABSTRACT: SARS-CoV-2 has recently been detected in feces, which indicates that wastewater may be used to monitor viral prevalence in the community. Here, we use RT-qPCR to monitor wastewater for SARS-CoV-2 RNA over a 74-day time course. We show that changes in SARS-CoV-2 RNA concentrations follow symptom onset gathered by retrospective interview of patients but precedes clinical test results. In addition, we determine a nearly complete (98.5%) SARS-CoV-2 genome sequence from wastewater and use phylogenetic analysis to infer viral ancestry. Collectively, this work demonstrates how wastewater can be used as a proxy to monitor viral prevalence in the community and how genome sequencing can be used for genotyping viral strains circulating in a community.

SUBMITTER: Nemudryi A 

PROVIDER: S-EPMC7457911 | biostudies-literature |

REPOSITORIES: biostudies-literature

Similar Datasets

| S-EPMC7276038 | biostudies-literature
| S-EPMC8497957 | biostudies-literature
| S-EPMC9355971 | biostudies-literature
| S-EPMC8361049 | biostudies-literature
| S-EPMC8278834 | biostudies-literature
| S-EPMC8702378 | biostudies-literature
| S-EPMC7568484 | biostudies-literature
| S-EPMC9596176 | biostudies-literature
| S-EPMC7938789 | biostudies-literature
| S-EPMC8832950 | biostudies-literature