Ontology highlight
ABSTRACT:
SUBMITTER: Kakuta Y
PROVIDER: S-EPMC7458277 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Kakuta Yoichi Y Kawai Yosuke Y Naito Takeo T Hirano Atsushi A Umeno Junji J Fuyuno Yuta Y Liu Zhenqiu Z Li Dalin D Nakano Takeru T Izumiyama Yasuhiro Y Ichikawa Ryo R Okamoto Daisuke D Nagai Hiroshi H Matsumoto Shin S Yamamoto Katsutoshi K Yokoyama Naonobu N Chiba Hirofumi H Shimoyama Yusuke Y Onodera Motoyuki M Moroi Rintaro R Kuroha Masatake M Kanazawa Yoshitake Y Kimura Tomoya T Shiga Hisashi H Endo Katsuya K Negoro Kenichi K Yasuda Jun J Esaki Motohiro M Tokunaga Katsushi K Nakamura Minoru M Matsumoto Takayuki T McGovern Dermot P B DPB Nagasaki Masao M Kinouchi Yoshitaka Y Shimosegawa Tooru T Masamune Atsushi A
Journal of Crohn's & colitis 20190401 5
<h4>Background and aims</h4>Genome-wide association studies [GWASs] of European populations have identified numerous susceptibility loci for Crohn's disease [CD]. Susceptibility genes differ by ethnicity, however, so GWASs specific for Asian populations are required. This study aimed to clarify the Japanese-specific genetic background for CD by a GWAS using the Japonica array [JPA] and subsequent imputation with the 1KJPN reference panel.<h4>Methods</h4>Two independent Japanese case/control sets ...[more]