A healthy lifestyle pattern and the risk of symptomatic gallstone disease: results from 2 prospective cohort studies.

ABSTRACT:

Background

Symptomatic gallstones cause high financial and disease burden for public health systems. The combined role of diet and other lifestyle factors has not been studied so far.

Objectives

We aimed to investigate the association between an a priori defined healthy lifestyle score (HLS, including healthy diet, moderate alcohol and regular coffee intakes, never smoking, physical activity, and normal weight) and the risk of symptomatic gallstone disease, and to estimate the proportion of cases potentially preventable by lifestyle modification.

Methods

We followed 60,768 women from the Nurses' Health Study (NHS) and 40,744 men from the Health Professionals Follow-up Study (HPFS), both ongoing prospective cohort studies, from baseline (1986) until 2012. Symptomatic g

SUBMITTER: Wirth J 

PROVIDER: S-EPMC7458768 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature