Ontology highlight
ABSTRACT:
SUBMITTER: Abdelhameed RFA
PROVIDER: S-EPMC7460232 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Abdelhameed Reda F A RFA Eltamany Enas E EE Hal Dina M DM Ibrahim Amany K AK AboulMagd Asmaa M AM Al-Warhi Tarfah T Youssif Khayrya A KA Abd El-Kader Adel M AM Hassanean Hashim A HA Fayez Shaimaa S Bringmann Gerhard G Ahmed Safwat A SA Abdelmohsen Usama Ramadan UR
Marine drugs 20200801 8
Bioactivity-guided fractionation of a methanolic extract of the Red Sea cucumber <i>Holothuria spinifera</i> and LC-HRESIMS-assisted dereplication resulted in the isolation of four compounds, three new cerebrosides, spiniferosides A (<b>1</b>), B (<b>2</b>), and C (<b>3</b>), and cholesterol sulfate (<b>4</b>). The chemical structures of the isolated compounds were established on the basis of their 1D NMR and HRMS spectral data. Metabolic profiling of the <i>H. spinifera</i> extract indicated th ...[more]