Ontology highlight
ABSTRACT:
SUBMITTER: Groeneweg KE
PROVIDER: S-EPMC7460577 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Groeneweg Koen E KE Duijs Jacques M G J JMGJ Florijn Barend W BW van Kooten Cees C de Fijter Johan W JW van Zonneveld Anton Jan AJ Reinders Marlies E J MEJ Bijkerk Roel R
International journal of molecular sciences 20200805 16
Acute rejection (AR) of a kidney graft in renal transplant recipients is associated with microvascular injury in graft dysfunction and, ultimately, graft failure. Circulating long noncoding RNAs (lncRNAs) may be suitable markers for vascular injury in the context of AR. Here, we first investigated the effect of AR after kidney transplantation on local vascular integrity and demonstrated that the capillary density markedly decreased in AR kidney biopsies compared to pre-transplant biopsies. Subse ...[more]