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Small RNAs, Big Diseases.


ABSTRACT: The past two decades have seen extensive research done to pinpoint the role of microRNAs (miRNAs) that have led to discovering thousands of miRNAs in humans. It is not, therefore, surprising to see many of them implicated in a number of common as well as rare human diseases. In this review article, we summarize the progress in our understanding of miRNA-related research in conjunction with different types of cancers and neurodegenerative diseases, as well as their potential in generating more reliable diagnostic and therapeutic approaches.

SUBMITTER: Rzeszutek I 

PROVIDER: S-EPMC7460979 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature

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Small RNAs, Big Diseases.

Rzeszutek Iwona I   Singh Aditi A  

International journal of molecular sciences 20200809 16


The past two decades have seen extensive research done to pinpoint the role of microRNAs (miRNAs) that have led to discovering thousands of miRNAs in humans. It is not, therefore, surprising to see many of them implicated in a number of common as well as rare human diseases. In this review article, we summarize the progress in our understanding of miRNA-related research in conjunction with different types of cancers and neurodegenerative diseases, as well as their potential in generating more re  ...[more]

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