Ontology highlight
ABSTRACT:
SUBMITTER: Balaskas P
PROVIDER: S-EPMC7461137 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Balaskas Panagiotis P Green Jonathan A JA Haqqi Tariq M TM Dyer Philip P Kharaz Yalda A YA Fang Yongxiang Y Liu Xuan X Welting Tim J M TJM Peffers Mandy J MJ
International journal of molecular sciences 20200807 16
Ageing is a leading risk factor predisposing cartilage to osteoarthritis. However, little research has been conducted on the effect of ageing on the expression of small non-coding RNAs (sncRNAs). RNA from young and old chondrocytes from macroscopically normal equine metacarpophalangeal joints was extracted and subjected to small RNA sequencing (RNA-seq). Differential expression analysis was performed in R using package DESeq2. For transfer RNA (tRNA) fragment analysis, tRNA reads were aligned to ...[more]